PRDM10 Products

Antibodies
PRDM10 Antibody
PRDM10 Antibody
NBP1-81427
Species: Hu
Applications: WB, ICC/IF, IHC, IHC-P
Host: Rabbit Polyclonal
PRDM10 Antibody
PRDM10 Antibody
NB100-1136
Species: Hu, Bv, Ca
Applications: PEP-ELISA
Host: Goat Polyclonal
Lysates
PRDM10 Overexpression Lysate ...
PRDM10 Overexpression Lysate (Native)
NBL1-14734
Applications: WB
Proteins
PRDM10 Recombinant Protein An ...
PRDM10 Recombinant Protein Antigen
NBP1-81427PEP
Species: Hu
Applications: AC
RNAi
PRDM10 RNAi
PRDM10 RNAi
H00056980-R02
Species: Hu
Applications: RNAi, RNAi SP
PRDM10 RNAi
PRDM10 RNAi
H00056980-R03
Species: Hu
Applications: RNAi, RNAi SP
PRDM10 RNAi
PRDM10 RNAi
H00056980-R01
Species: Hu
Applications: RNAi, RNAi SP

Description

Similar to acetylation and phosphorylation, histone methylation at the N-terminal tail has emerged as an important role in regulating chromatin dynamics and gene activity. Histone methylation occurs on arginine and lysine residues and is catalyzed by two families of proteins, the protein arginine methyltransferase family and the SET-domain-containing methyltransferase family. Five members have been identified in the arginine methyltransferase family. About 27 are grouped into the SET-domain family, and another 17 make up the PR domain family that is related to the SET domain family. The retinoblastoma protein-interacting zinc finger gene RIZ 1 is a tumor suppressor gene and a FOUNDING member of the PR domain family. RIZ 1 inactivation is commonly found in many types of human cancers and occurs through loss of mRNA expression, frame shift mutation, chromosomal deletion, and missense mutation. RIZ 1 is also a tumor susceptibility gene in mice. The loss of RIZ 1 mRNA in human cancers was shown to associate with DNA methylation of its promoter CpG island. Methylation of the RIZ 1 promoter strongly correlated with lost or decreased RIZ 1 mRNA expression in breast, liver, colon, and lung cancer cell lines as well as in liver cancer tissues.

Bioinformatics

Entrez Human
Uniprot Human
Human
Human
Product By Gene ID 56980
Alternate Names
  • PR domain zinc finger protein 10
  • Tristanin
  • PR domain-containing protein 10
  • TRIS
  • MGC131802
  • PFM7tristanin
  • KIAA1231PRDM zinc finger transcription factor
  • PR-domain family member 7
  • PR domain containing 10

Diseases related to PRDM10

Discover more about diseases related to PRDM10.

Gangliosidoses
Severe Mental Retardation
Crest Syndrome
Gangliosidoses, Gm2

Pathways for PRDM10

View related products by pathway and learn more about each of the pathways below.

Pathogenesis
Localization
Chromatin Remodeling

Research Areas for PRDM10

Find related products by research area and learn more about each of the different research areas below.

Chromatin Research

Bioinformatics Tool for PRDM10

Discover related pathways, diseases and genes to PRDM10. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
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