PMCA2 Products

Antibodies
PMCA2 Antibody
PMCA2 Antibody
NB120-3529
Species: Hu, Rt, Po
Applications: WB, ELISA, IHC-Fr, IHC-P
Host: Rabbit Polyclonal
RNAi
PMCA2 RNAi
PMCA2 RNAi
H00000491-R03
Species: Hu
Applications: RNAi, RNAi SP
PMCA2 RNAi
PMCA2 RNAi
H00000491-R04
Species: Hu
Applications: RNAi, RNAi SP

Description

The protein encoded by the PMCA2 gene belongs to the family of P-type primary ion transport ATPases characterized by the formation of an aspartyl phosphate intermediate during the reaction cycle. These enzymes remove bivalent calcium ions from eukaryotic cells against very large concentration gradients and play a critical role in intracellular calcium homeostasis. The mammalian plasma membrane calcium ATPase isoforms are encoded by at least four separate genes and the diversity of these enzymes is further increased by alternative splicing of transcripts. The expression of different isoforms and splice variants is regulated in a developmental, tissue- and cell type-specific manner, suggesting that these pumps are functionally adapted to the physiological needs of particular cells and tissues. This gene encodes the plasma membrane calcium ATPase isoform 2. Alternatively spliced transcript variants encoding different isoforms have been identified. (provided by RefSeq)

Bioinformatics

Entrez Human
Product By Gene ID 491
Alternate Names
  • plasma membrane calcium-transporting ATPase 2
  • PMCA2i
  • PMCA2a
  • PMCA2
  • ATPase, Ca++ transporting, plasma membrane 2

PTMs for PMCA2

Learn more about PTMs related to PMCA2.

Phosphorylation
Biotinylation

Bioinformatics Tool for PMCA2

Discover related pathways, diseases and genes to PMCA2. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
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