PICK1 Products

Antibodies
PICK1 Antibody
PICK1 Antibody
NBP1-42829
Species: Mu, Rt
Applications: WB, ICC/IF, IHC, IHC-P, IP
Host: Chicken Polyclonal
PICK1 Antibody
PICK1 Antibody
NB120-3420
Species: Mu, Rt
Applications: WB, IP, ICC, IF
Host: Rabbit Polyclonal
PICK1 Antibody
PICK1 Antibody
NB100-41403
Species: Mu, Rt
Applications: WB, PEP-ELISA
Host: Goat Polyclonal
Antibody Pairs
PICK1 Antibody Pair
PICK1 Antibody Pair
H00009463-PW2
Species: Hu
Applications: WB, IP
Lysates
PICK1 Overexpression Lysate ( ...
PICK1 Overexpression Lysate (Denat...
H00009463-T01
Species: Hu
Applications: WB
PICK1 Overexpression Lysate ( ...
PICK1 Overexpression Lysate (Native)
NBP2-08579
Applications: WB
PICK1 Overexpression Lysate ( ...
PICK1 Overexpression Lysate (Native)
NBP2-07450
Applications: WB
Proteins
PICK1 Recombinant Protein
PICK1 Recombinant Protein
NBP2-51934
Species: Hu
Applications: PAGE
RNAi
PICK1 RNAi
PICK1 RNAi
H00009463-R02
Species: Hu
PICK1 RNAi
PICK1 RNAi
H00009463-R03
Species: Hu
PICK1 RNAi
PICK1 RNAi
H00009463-R01
Species: Hu

Description

PSD-95/DLG/ZO-1 (PDZ) domain-containing proteins play a central role in synaptic membrane protein localization. The protein interacting with protein kinase C (PICK 1) is a synaptic PDZ domain protein that also contains a coiled-coil and acidic domain. Studies indicate that PICK 1 functions as a targeting and transport protein and has been shown to interact with protein kinase C alpha (PKC alpha), AMPA-type glutamate receptors, and several other membrane receptors via its PDZ domain. The interaction of PICK 1 with PKC alpha is highly dependent on the activation of the kinase. It appears that PICK 1 directs the activated form of PKC alpha to membrane anchored GluR2. Once phosphorylated by PKC alpha, GluR2 is released from the synaptic anchor proteins. Once released, GluR2 is transported from the synaptic membrane in a PICK 1-dependent manner.

Bioinformatics

Entrez Human
Mouse
Rat
Uniprot Human
Human
Human
Human
Human
Rat
Product By Gene ID 9463
Alternate Names
  • Protein kinase C-alpha-binding protein
  • PRKCA-binding protein
  • Protein interacting with C kinase 1
  • PICK
  • alpha binding protein
  • MGC15204
  • PRKCABPprotein interacting with PRKCA
  • dJ1039K5
  • protein interacting with PRKCA 1

Research Areas for PICK1

Find related products by research area and learn more about each of the different research areas below.

Signal Transduction
Transcription Factors and Regulators
Vision

Bioinformatics Tool for PICK1

Discover related pathways, diseases and genes to PICK1. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
Vizit™, under license from BioVista Inc.