PICK1 Products

Antibodies
PICK1 Antibody
PICK1 Antibody
NB100-41403
Species: Hu, Mu, Rt
Applications: WB, IHC, IHC-P, PEP-ELISA
Host: Goat Polyclonal
PICK1 Antibody
PICK1 Antibody
NB120-3420
Species: Mu, Rt
Applications: WB, ICC/IF, IP
Host: Rabbit Polyclonal
PICK1 Antibody (JG30-80)
PICK1 Antibody (JG30-80)
NBP2-76863
Species: Hu, Mu, Rt
Applications: WB, Flow, IP
Host: Rabbit Monoclonal
Lysates
PICK1 Overexpression Lysate
PICK1 Overexpression Lysate
NBP2-09205
Species: Hu
Applications: WB
PICK1 Overexpression Lysate
PICK1 Overexpression Lysate
NBP2-08579
Species: Hu
Applications: WB
PICK1 Overexpression Lysate
PICK1 Overexpression Lysate
NBP2-07450
Species: Hu
Applications: WB
Proteins
Recombinant Human PICK1 Prote ...
Recombinant Human PICK1 Protein
NBP2-51934
Species: Hu
Applications: PAGE
PICK1 Recombinant Protein Ant ...
PICK1 Recombinant Protein Antigen
NBP2-57605PEP
Species: Hu
Applications: AC
PICK1 Recombinant Protein Ant ...
PICK1 Recombinant Protein Antigen
NBP2-57239PEP
Species: Hu
Applications: AC

Description

PSD-95/DLG/ZO-1 (PDZ) domain-containing proteins play a central role in synaptic membrane protein localization. The protein interacting with protein kinase C (PICK 1) is a synaptic PDZ domain protein that also contains a coiled-coil and acidic domain. Studies indicate that PICK 1 functions as a targeting and transport protein and has been shown to interact with protein kinase C alpha (PKC alpha), AMPA-type glutamate receptors, and several other membrane receptors via its PDZ domain. The interaction of PICK 1 with PKC alpha is highly dependent on the activation of the kinase. It appears that PICK 1 directs the activated form of PKC alpha to membrane anchored GluR2. Once phosphorylated by PKC alpha, GluR2 is released from the synaptic anchor proteins. Once released, GluR2 is transported from the synaptic membrane in a PICK 1-dependent manner.

Bioinformatics

Entrez Human
Mouse
Rat
Uniprot Human
Human
Human
Human
Human
Rat
Product By Gene ID 9463
Alternate Names
  • Protein kinase C-alpha-binding protein
  • PRKCA-binding protein
  • Protein interacting with C kinase 1
  • PICK
  • alpha binding protein
  • MGC15204
  • PRKCABPprotein interacting with PRKCA
  • dJ1039K5
  • protein interacting with PRKCA 1

Research Areas for PICK1

Find related products by research area and learn more about each of the different research areas below.

Signal Transduction
Transcription Factors and Regulators
Vision

Bioinformatics Tool for PICK1

Discover related pathways, diseases and genes to PICK1. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
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