PHEX Products

Description

The protein encoded by the PHEX gene is a transmembrane endopeptidase that belongs to the type II integral membrane zinc-dependent endopeptidase family. The protein is thought to be involved in bone and dentin mineralization and renal phosphate reabsorption. Mutations in this gene cause X-linked hypophosphatemic rickets. (provided by RefSeq)

Bioinformatics

Uniprot	NP_000435.3 Human
Product By Gene ID	5251
Alternate Names	EC 3.4.24.- HPDR HPDR1X-linked hypophosphatemia protein HYP1 HYPLXHR Metalloendopeptidase homolog PEX PEXVitamin D-resistant hypophosphatemic rickets protein phosphate regulating endopeptidase homolog, X-linked phosphate regulating gene with homologies to endopeptidases on the X chromosome(hypophosphatemia, vitamin D resistant rickets) phosphate-regulating neutral endopeptidase XLH