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1159-SB) stimulates proliferation in the NR6R-3T3 mouse fibroblast cell line in a dose-dependent manner (orange line). Proliferation elicited by Recombinant Human PDGF-DD (0.75 ug/mL) is neutralized (green line) by increasing concentrations of Mouse Anti-Human PDGF-D Monoclonal Antibody (Catalog # MAB1159). The ND50 is typically 1.5-7.5 µg/mL." class="big_lightbox" target="_blank">
SCDGFB is encoded by this gene is a member of the platelet-derived growth factor family. The four members of this family are mitogenic factors for cells of mesenchymal origin and are characterized by a core motif of eight cysteines, seven of which are found in this factor. This gene product only forms homodimers and, therefore, does not dimerize with the other three family members. It differs from alpha and beta members of this family in having an unusual N-terminal domain, the CUB domain. Two splice variants have been identified for this gene. [provided by RefSeq]
![Western Blot PDGF-D/SCDGFB Antibody [Unconjugated]](http://images.novusbio.com/fullsize/af1159_human-pdgf-d-affinity-purified-polyclonal-ab-8120255552881.jpg)
![Bioactivity PDGF-D/SCDGFB [Unconjugated]](http://images.novusbio.com/fullsize/protein/PDGFD_9738SB_1892.jpg)
