PCDHGB6 Products

Antibodies
PCDHGB6 Antibody - Azide and ...
PCDHGB6 Antibody - Azide and BSA Free
H00056100-B01P
Species: Hu
Applications: WB
Host: Mouse Polyclonal
Proteins
Recombinant Human PCDHGB6 GST ...
Recombinant Human PCDHGB6 GST (N-T...
H00056100-P01
Species: Hu
Applications: WB, ELISA, MA, AP

Description

PCDHGB6 is a member of the protocadherin gamma gene cluster, one of three related clusters tandemly linked on chromosome five. These gene clusters have an immunoglobulin-like organization, suggesting that a novel mechanism may be involved in their regulation and expression. The gamma gene cluster includes 22 genes divided into 3 subfamilies. Subfamily A contains 12 genes, subfamily B contains 7 genes and 2 pseudogenes, and the more distantly related subfamily C contains 3 genes. The tandem array of 22 large, variable region exons are followed by a constant region, containing 3 exons shared by all genes in the cluster. Each variable region exon encodes the extracellular region, which includes 6 cadherin ectodomains and a transmembrane region. The constant region exons encode the common cytoplasmic region. These neural cadherin-like cell adhesion proteins most likely play a critical role in the establishment and function of specific cell-cell connections in the brain. Alternative splicing has been described for the gamma cluster genes. [provided by RefSeq]

Bioinformatics

Uniprot Human
Human
Product By Gene ID 56100
Alternate Names
  • PCDH-gamma-B6
  • PCDH-GAMMA-B6
  • protocadherin gamma subfamily B, 6
  • protocadherin gamma-B6