PCDHGA5 Products

Antibodies
PCDHGA5 Antibody (5H5)
PCDHGA5 Antibody (5H5)
H00056110-M01
Species: Hu
Applications: WB, ELISA
Host: Mouse Monoclonal
PCDHGA5 Antibody
PCDHGA5 Antibody
NBP2-43756
Species: Hu, Pm
Applications: WB
Host: Rabbit Polyclonal
PCDHGA5 Antibody
PCDHGA5 Antibody
H00056110-B01P
Species: Hu
Applications: WB
Host: Mouse Polyclonal
Lysates
PCDHGA5 Overexpression Lysate ...
PCDHGA5 Overexpression Lysate
NBP2-06084
Species: Hu
Applications: WB
Proteins
Recombinant Human PCDHGA5 GST ...
Recombinant Human PCDHGA5 GST (N-T...
H00056110-P01
Species: Hu
Applications: WB, ELISA, MA, AP
Recombinant Human PCDHGA5 GST ...
Recombinant Human PCDHGA5 GST (N-T...
H00056110-Q01
Species: Hu
Applications: WB, ELISA, MA, AP

Description

PCDHGA5 is a member of the protocadherin gamma gene cluster, one of three related clusters tandemly linked on chromosome five. These gene clusters have an immunoglobulin-like organization, suggesting that a novel mechanism may be involved in their regulation and expression. The gamma gene cluster includes 22 genes divided into 3 subfamilies. Subfamily A contains 12 genes, subfamily B contains 7 genes and 2 pseudogenes, and the more distantly related subfamily C contains 3 genes. The tandem array of 22 large, variable region exons are followed by a constant region, containing 3 exons shared by all genes in the cluster. Each variable region exon encodes the extracellular region, which includes 6 cadherin ectodomains and a transmembrane region. The constant region exons encode the common cytoplasmic region. These neural cadherin-like cell adhesion proteins most likely play a critical role in the establishment and function of specific cell-cell connections in the brain. Alternative splicing has been described for the gamma cluster genes.

Bioinformatics

Uniprot Human
Human
Human
Alternate Names
  • cadherin ME3
  • CDH-GAMMA-A5
  • ME3
  • MGC142020
  • PCDH-gamma-A5
  • PCDH-GAMMA-A5
  • protocadherin gamma subfamily A, 5
  • protocadherin gamma-A5

Research Areas for PCDHGA5

Find related products by research area and learn more about each of the different research areas below.

Neuroscience