PCDHA10 Products

Antibodies
PCDHA10 Antibody (1F6) - Azid ...
PCDHA10 Antibody (1F6) - Azide and...
H00056139-M01
Species: Hu
Applications: WB, ELISA, IHC
Host: Mouse Monoclonal
PCDHA10 Antibody
PCDHA10 Antibody
NBP2-19721
Species: Hu
Applications: WB
Host: Rabbit Polyclonal
PCDHA10 Antibody - BSA Free
PCDHA10 Antibody - BSA Free
NBP1-59258
Species: Hu
Applications: WB
Host: Rabbit Polyclonal
Lysates
PCDHA10 Overexpression Lysate ...
PCDHA10 Overexpression Lysate
NBP2-06114
Species: Hu
Applications: WB

Description

PCDHA10 is a member of the protocadherin alpha gene cluster, one of three related gene clusters tandemly linked on chromosome five that demonstrate an unusual genomic organization similar to that of B-cell and T-cell receptor gene clusters. The alpha gene cluster is composed of 15 cadherin superfamily genes related to the mouse CNR genes and consists of 13 highly similar and 2 more distantly related coding sequences. The tandem array of 15 N-terminal exons, or variable exons, are followed by downstream C-terminal exons, or constant exons, which are shared by all genes in the cluster. The large, uninterrupted N-terminal exons each encode six cadherin ectodomains while the C-terminal exons encode the cytoplasmic domain. These neural cadherin-like cell adhesion proteins are integral plasma membrane proteins that most likely play a critical role in the establishment and function of specific cell-cell connections in the brain. Alternative splicing has been observed and additional variants have been suggested but their full-length nature has yet to be determined.

Bioinformatics

Uniprot Human
Human
Human
Human
Human
Product By Gene ID 56139
Alternate Names
  • CNR8
  • CNRN8
  • CNRS8
  • CRNR8
  • KIAA0345-like 4
  • ortholog to mouse CNR8
  • PCDH-ALPHA10
  • PCDH-alpha-10
  • protocadherin alpha 10
  • protocadherin alpha-10