Species: Hu
Applications: WB, IHC
Host: Rabbit Polyclonal
Species: Hu
Applications: WB, ICC/IF, IHC
Host: Mouse Polyclonal
Species: Hu
Applications: IHC
Host: Rabbit Polyclonal
Species: Hu
Applications: WB
Species: Hu
Applications: WB, ELISA, MA, AP
Species: Hu
Applications: AC
Species: Hu
Applications: AC
Description
Sulfation is a common modification of endogenous (lipids, proteins, and carbohydrates) and exogenous (xenobiotics and drugs) compounds. In mammals, the sulfate source is 3'-phosphoadenosine 5'-phosphosulfate (PAPS), created from ATP and inorganic sulfate. Two different tissue isoforms encoded by different genes synthesize PAPS. This gene encodes one of the two PAPS synthetases. Defects in this gene cause the Pakistani type of spondyloepimetaphyseal dysplasia. Two alternatively spliced transcript variants that encode different isoforms have been described for this gene.
Bioinformatics
Uniprot |
Human Human Human Human Human |
Product By Gene ID |
9060 |
Alternate Names |
- 3'-phosphoadenosine 5'-phosphosulfate synthase 2
- ATP sulfurylase/adenosine 5'-phosphosulfate kinase
- ATPSK2ATP sulfurylase/APS kinase 2
- bifunctional 3'-phosphoadenosine 5'-phosphosulfate synthase 2
- bifunctional 3'-phosphoadenosine 5'-phosphosulfate synthethase 2
- EC 2.7.1.25
- PAPS synthase 2
- PAPS synthetase 2
- PAPSS 2
- SK 2
- SK2
- Sulfurylase kinase 2,3-prime-phosphoadenosine 5-prime-phosphosulfate synthase 2
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Research Areas for PAPSS2
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Stem Cell Markers