pan-Synuclein Products

pan-Synuclein Antibody
pan-Synuclein Antibody
Species: Hu, Mu, Rt
Applications: WB, IHC, IHC-P
Host: Rabbit Polyclonal
pan-Synuclein Recombinant Pro ...
pan-Synuclein Recombinant Protein ...
Species: Hu
Applications: AC
Recombinant Mouse pan-Synucle ...
Recombinant Mouse pan-Synuclein Pr...
Species: Mu
Applications: PAGE


Alpha synuclein is an abundant 140 amino acid neuronal protein, expressed primarily at presynaptic terminals in the central nervous system. Alpha synuclein has been associated with several neurodegenerative diseases. A point mutation in the gene coding for the alpha-synuclein protein was the first discovery linking this protein to a rare familial form of Parkinson's disease (PD). Subsequently, other mutations in the alpha-synuclein gene have been identified in familial PD. The aggregated proteinaceous inclusions called Lewy bodies found in PD and cortical Lewy body dementia (LBD) were discovered to be predominantly alpha-synuclein. Aberrant aggregation of alpha-synuclein has been detected in an increasing number of neurodegenerative diseases, collectively known as synucleopathies. Alpha-synuclein exists physiologically in both soluble and membrane-bound states, in unstructured and alpha-helical conformations, respectively. The physiological function of alpha-synuclein appears to require its translocation between these subcellular compartments and interconversion between the 2 conformations. Abnormal processing of alpha-synuclein is predicted to lead to pathological changes in its binding properties and function (1).


Uniprot Human
Product By Gene ID 6622
Alternate Names
  • MGC110988
  • Non-A4 component of amyloid precursor
  • PARK4
  • non-A4 component of amyloid
  • Non-A beta component of AD amyloid
  • non A-beta component of AD amyloid
  • Lewy body) 4
  • synuclein, alpha (non A4 component of amyloid precursor)

Research Areas for pan-Synuclein

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Alzheimers Research
Cell Biology
Cytoskeleton Markers
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Stem Cell Markers

Bioinformatics Tool for pan-Synuclein

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