p130 Products

Antibodies
p130 Antibody
p130 Antibody
NBP1-82455
Species: Hu, Mu, Rt
Applications: WB, ICC/IF, IHC, IHC-P
Host: Rabbit Polyclonal
p130 Antibody (130P215)
p130 Antibody (130P215)
NB600-1541
Species: Hu, Rt
Applications: IHC, IHC-P
Host: Mouse Monoclonal
Lysates
p130 Overexpression Lysate (N ...
p130 Overexpression Lysate (Native)
NBL1-15193
Applications: WB
Proteins
p130 Partial Recombinant Prot ...
p130 Partial Recombinant Protein
H00005934-Q01
Species: Hu
Applications: WB, ELISA, PA
p130 Recombinant Protein Anti ...
p130 Recombinant Protein Antigen
NBP1-82455PEP
Species: Hu
Applications: AC
RNAi
p130 RNAi
p130 RNAi
H00005934-R01
Species: Hu

Description

Two retinoblastoma related proteins, p107 and pRb2 / p130, which are structurally and functionally similar to the product of the retinoblastoma gene (pRb / p105), were cloned by taking advantage of their ability to bind transforming proteins of DNA tumor viruses through a particular region called the "pocket domain." Like pRb, both proteins play a fundamental role in growth control. These Rb family proteins were measured in a variety of lung neoplasms. The highest percentage of undetectable levels and the tightest inverse correlation with the histological grading and with PCNA expression in the most aggressive tumor types were found for pRb2 / p130, which may suggest an important role for this protein in the pathogenesis and progression of lung cancer.

Bioinformatics

Uniprot Human
Human
Human
Human
Human
Product By Gene ID 5934
Alternate Names
  • pRb2
  • RBR-2
  • RB2
  • retinoblastoma-like protein 2,130 kDa retinoblastoma-associated protein
  • Retinoblastoma-related protein 2
  • PRB2
  • p130
  • P130
  • Rb2
  • FLJ26459
  • retinoblastoma-like 2 (p130)

Research Areas for p130

Find related products by research area and learn more about each of the different research areas below.

Apoptosis
Cancer
Phospho-Specific
Tumor Suppressors

Bioinformatics Tool for p130

Discover related pathways, diseases and genes to p130. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
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