Species: Ec
Applications: PAGE
Description
nfnB, also known as NFSB, shows the ability to reduce quinines. nfnB is an enzyme for activating prodrugs in antibody directed enzyme prodrug therapy. nfnB is also capable of reducing nitrofurazone, quinones and the anti-tumor agent CB1954 (5-(aziridin-1-yl)-2,4-dinitrobenzamide). The reduction of CB1954 results in the generation of cytotoxic species.
Bioinformatics