Species: Hu
Applications: WB, ICC/IF
Host: Rabbit Polyclonal
Species: Hu
Applications: WB, ELISA, IHC, IP
Host: Rabbit Polyclonal
Species: Hu, Mu, Rt
Applications: WB, ICC/IF
Host: Rabbit Polyclonal
Species: Hu
Applications: WB
Species: Hu
Applications: AC
Species: Hu
Applications: AC
Species: Hu
Applications: AC
Description
Metalloprotease that specifically deubiquitinates monoubiquitinated histone H2A, a specific tag for epigenetic transcriptional repression, thereby acting as a coactivator. Preferentially deubiquitinates monoubiquitinated H2A in hyperacetylated nucleosomes. Deubiquitination of histone H2A leads to facilitate the phosphorylation and dissociation of histone H1 from the nucleosome. Acts as a coactivator by participating in the initiation and elongation steps of androgen receptor (AR)-induced gene activation.
Bioinformatics
| Uniprot |
Human
|
| Product By Gene ID |
114803 |
| Alternate Names |
- DKFZp779J1554
- DKFZp779J1721,2A-DUB
- histone H2A deubiquitinase MYSM1
- KIAA1915
- Myb-like, SWIRM and MPN domains 1,2ADUB
- RP4-592A1.1
- SWIRM and MPN domain-containing protein 1
|
