Myelin Products


Description

Myelin is produced by oligodendrocytes in the CNS and Schwann cells in the peripheral nervous system (PNS). Defining the differences between CNS and PNS myelin may provide insights into the process of myelination and the pathogenesis of certain idiopathic diseases involving myelin such as multiple sclerosis, certain leukodystrophies, and other myelinopathies. Myelin is composed of about 80% lipid fat and about 20% protein. Some of the proteins that make up myelin are Myelin basic protein (MBP), Myelin oligodendrocyte glycoprotein (MOG) and Proteolipid protein (PLP). Myelin is made up primarily of a glycolipid called galactocerebroside. The intertwining of the hydrocarbon chains of sphingomyelin serve to strengthen the myelin sheath.

Bioinformatics

Product By Gene ID 4340
Alternate Names
  • MGC26137
  • MOG Ig-AluB
  • MOGIG2
  • myelin oligodendrocyte glycoprotein
  • myelin-oligodendrocyte glycoprotein

Research Areas for Myelin

Find related products by research area and learn more about each of the different research areas below.

Stem Cell Markers

Related Myelin Blog Posts

Check out the latest blog posts on Myelin.
Phagocytes in Multiple Sclerosis: Myelin uptake leads to oxysterol-induced activation of liver X receptors, LXRs
By Jamshed Arslan Pharm.D., PhD.Myelin is a cholesterol-rich layer around nerves. Damage to this protective layer and the consequent slowing down of nerve impulses are hallmarks of multiple sclerosis (MS) and other ...    Read more.
Read more Myelin related blogs.