MTGR1 Products

Antibodies
MTGR1 Antibody
MTGR1 Antibody
NBP2-34136
Species: Hu
Applications: WB, IHC, IHC-P
Host: Rabbit Polyclonal
MTGR1 Antibody (2C10)
MTGR1 Antibody (2C10)
H00009139-M15
Species: Hu
Applications: WB, ELISA, IHC, IHC-P
Host: Mouse Monoclonal
MTGR1 Antibody
MTGR1 Antibody
H00009139-B01P
Species: Hu
Applications: WB, ELISA, ICC/IF
Host: Mouse Polyclonal
Lysates
MTGR1 Overexpression Lysate ( ...
MTGR1 Overexpression Lysate (Native)
NBL1-08734
Applications: WB
MTGR1 Overexpression Lysate ( ...
MTGR1 Overexpression Lysate (Denat...
H00009139-T01
Species: Hu
Applications: WB
Proteins
MTGR1 Recombinant Protein Ant ...
MTGR1 Recombinant Protein Antigen
NBP2-56057PEP
Species: Hu
Applications: B/N, Ctrl
Recombinant Human MTGR1 Prote ...
Recombinant Human MTGR1 Protein
H00009139-P01
Species: Hu
Applications: WB, ELISA, PA
Recombinant Human MTGR1 Prote ...
Recombinant Human MTGR1 Protein
H00009139-Q01
Species: Hu
Applications: WB, ELISA, PA
RNAi
MTGR1 RNAi
MTGR1 RNAi
H00009139-R02
Species: Hu
Applications: RNAi, RNAi SP
MTGR1 RNAi
MTGR1 RNAi
H00009139-R01
Species: Hu
Applications: RNAi, RNAi SP
MTGR1 RNAi
MTGR1 RNAi
H00009139-R03
Species: Hu
Applications: RNAi, RNAi SP

Description

In acute myeloid leukemia, especially in the M2 subtype, the t(8;21)(q22;q22) translocation is one of the most frequent karyotypic abnormalities. The translocation produces a chimeric gene made up of the 5'-region of the RUNX1 (AML1) gene fused to the 3'-region of the CBFA2T1 (MTG8) gene. The chimeric protein is thought to associate with the nuclear corepressor/histone deacetylase complex to block hematopoietic differentiation. The protein encoded by this gene binds to the AML1-MTG8 complex and may be important in promoting leukemogenesis. Several transcript variants are thought to exist for this gene, but the full-length natures of only three have been described.

Bioinformatics

Entrez Human
Uniprot Human
Human
Human
Human
Human
Product By Gene ID 9139
Alternate Names
  • protein CBFA2T2
  • MTG8-like protein
  • myeloid translocation gene-related protein 1
  • ETO homologous on chromosome 20
  • ETO homolog on chromosome 20
  • Myeloid translocation-related protein 1
  • ZMYND3
  • EHTDKFZp313F2116
  • MTGR1p85
  • MTG8-related protein 1
  • core-binding factor, runt domain, alpha subunit 2; translocated to, 2

Pathways for MTGR1

View related products by pathway and learn more about each of the pathways below.

Cell Proliferation
Wound Healing

Research Areas for MTGR1

Find related products by research area and learn more about each of the different research areas below.

Cancer
Tumor Suppressors

Bioinformatics Tool for MTGR1

Discover related pathways, diseases and genes to MTGR1. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
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