MT-ND1 Products

Antibodies
MT-ND1 Antibody
MT-ND1 Antibody
NBP1-68576
Species: Hu
Applications: WB, ELISA, IHC, IHC-P
Host: Rabbit Polyclonal
Proteins
MT-ND1 Partial Recombinant Pr ...
MT-ND1 Partial Recombinant Protein
H00004535-Q01
Species: Hu
Applications: WB, ELISA, PA

Description

NADH:ubiquinone oxidoreductase (complex I) is an extremely complicated multiprotein complex located in the inner mitochondrial membrane. Human complex I is important for energy metabolism because its main function is to transport electrons from NADH to ubiquinone, which is accompanied by translocation of protons from the mitochondrial matrix to the intermembrane space. Human complex I appears to consist of 41 subunits. A small number of complex I subunits are the products of mitochondrial genes (subunits 1-7),while the remainder are nuclear encoded and imported from the cytoplasm. NADH dehydrogenase subunit 1 (ND1) binds rotenone and rotenone analogs and might be involved in electron transfer to ubiquinone. Mutations in the ND1 gene may be implicated in several disorders, including Leber hereditary optic neuropathy, Alzheimer's disease and Parkinson disease.

Bioinformatics

Entrez Human
Uniprot Human
Human
Product By Gene ID 4535
Alternate Names
  • EC 1.6.5.3
  • NADH1
  • NADH dehydrogenase subunit 1
  • NADH dehydrogenase, subunit 1 (complex I)
  • MTND1
  • ND1NADH dehydrogenase 1
  • NAD1
  • mitochondrially encoded NADH dehydrogenase 1

Bioinformatics Tool for MT-ND1

Discover related pathways, diseases and genes to MT-ND1. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
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