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MRPL20, also known as 39 S ribosomal protein L20, mitochondrial, is a 17.4 kDa, 149 amino acid protein that is involved in protein synthesis in the mitochondria. Diseases and disorders such as malaria, mycobacterium tuberculosis, pneumonia, and tuberculosis are being researched with this protein. The protein interacts with CALM3, EPS8, CALM1, DUSP23, and CALM2.