Description
Three types of opioid receptors have been cloned -- mu, delta, and kappa. Opioid receptors are seven transmembrane G-protein coupled receptors. They share a high degree of homology and are most divergent at the N- and C-termini. Activation of mu opioid receptors leads to a decrease in neuronal excitability. Several C-terminal splice variants have been identified for the Mu Opioid Receptor (MOR1) including MOR1C. These splice variants appear to differ in their pharmacological selectivity as well as their membrane trafficking.
Bioinformatics
| Entrez |
Mouse
Rat
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| Alternate Names |
- mu 1
- mu opioid receptor mor1o; mor1; mu opiate receptor; kiaa0403; opioid receptor mu 1; mu opioid receptor; oprm; mutype opioid receptor; opioid receptor
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