MMP26 Products

Antibodies
MMP26 Antibody (3B9)
MMP26 Antibody (3B9)
H00056547-M02
Species: Hu
Applications: WB, ELISA, ICC/IF
Host: Mouse Monoclonal
MMP26 Antibody (6C6)
MMP26 Antibody (6C6)
H00056547-M01
Species: Hu
Applications: WB, ELISA
Host: Mouse Monoclonal
MMP26 Antibody (3B9)
MMP26 Antibody (3B9)
H00056547-M02A-200ul
Species: Hu
Applications: WB, ELISA
Host: Mouse Monoclonal
Lysates
MMP26 Overexpression Lysate ( ...
MMP26 Overexpression Lysate (Native)
NBL1-13158
Applications: WB
Proteins
MMP26 Partial Recombinant Pro ...
MMP26 Partial Recombinant Protein
H00056547-Q01
Species: Hu
Applications: WB, ELISA, PA
RNAi
MMP26 RNAi
MMP26 RNAi
H00056547-R01
Species: Hu
Applications: RNAi, RNAi SP

Description

Matrix metalloproteinase 26 (MMP-26) is specifically expressed in cancer cells of epithelial origin, including carcinomas of lung, prostate and breast. Several unique structural and regulatory features, including an unusual 'cysteine-switch' motif, discriminate broad-spectrum MMP-26 from most other MMPs. MMP-26 efficiently cleaves fibrinogen and extracellular matrix proteins, including fibronectin, vitronectin and denatured collagen (1). Expression analysis revealed that matrilysin-2 is detected not only in placenta and uterus but is widely expressed in malignant tumors from different sources as well as in diverse tumor cell lines. These data together with its broad spectrum of proteolytic activity, suggest that MMP-26 may play a role in some of the tissue-remodeling events associated with tumor progression (2). A study of MMP-26 mRNA steady states levels reveals, among the tissue examined, a specific expression in placenta. MMP-26 mRNA could also be detected in several human cell lines such as HEK 293 kidney cells and HFB1 lymphoma cells (3)

Bioinformatics

Entrez Human
Uniprot Human
Human
Human
Human
Product By Gene ID 56547
Alternate Names
  • Matrilysin-2
  • MMP-26
  • Endometase
  • matrix metalloproteinase 26
  • EC 3.4.24.-
  • endometase
  • matrix metalloproteinase-26
  • MGC126592
  • matrilysin-2
  • MGC126590
  • matrilysin 2
  • matrix metallopeptidase 26

PTMs for MMP26

Learn more about PTMs related to MMP26.

Cleavage
Phosphorylation

Bioinformatics Tool for MMP26

Discover related pathways, diseases and genes to MMP26. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
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