MHC Class I RT1Au Products

MHC Class I RT1Au Antibody (N ...
MHC Class I RT1Au Antibody (NR3/31)
Species: Rt
Applications: Flow
Host: Rat Monoclonal


MHC Class I molecules play a central role in the immune system by presenting peptides derived from the endoplasmic reticulum lumen. MHC class I antigens are heterodimers consisting of one alpha chain (44kDa) with beta 2 microglobulin (11.5 kDa). The antigen is expressed by all somatic cells at varying levels. MHC Class I molecules are expressed on most nucleated cells where they present endogenously synthesized antigenic peptides to CD8+ T lymphocytes, which are usually cytotoxic T cells. Fibroblasts or neurons however only show a low level of antigen.

Research Areas for MHC Class I RT1Au

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Adaptive Immunity
Major Histocompatibility Complexes