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LZTS2, also known as leucine zipper putative tumor suppressor 2, is a 72.8 kDa, 669 amino acid protein that is involved in formation of the central spindle during cytokinesis. Current research is being conducted to link the protein to diseases such as ataxia, breast cancer, prostatitis, and Alzheimer's disease. The protein interacts in mitosis and cell division pathways with other proteins such as NINL, CCDC85B, RHOXF2, RBPMS, and ZNF512B.
