Species: Hu, Rt
Applications: WB, Simple Western
Description
Nasal NK/T-cell lymphoma (NL) affects mostly Oriental populations, due to epigenetic modification that seem isolated to this ethnic group. CADM1 is silenced in NL, while its tumor suppressor partner EPB41L3 seems unchanged. Similar effects are seen in non-Hodgkin lymphoma, indicating that analysis of these targets can differentiate early lymphomas from normal cells.
Research Areas for Lymphoma Markers
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Cancer