LRP5/6 Products

Antibodies
LRP5/6 Antibody
LRP5/6 Antibody
NBP1-45687
Species: Hu, Mu, Rt
Applications: WB
Host: Rabbit Polyclonal

Description

LDL related proteins, LRP 5 and LRP 6, are members of the LDL receptor superfamily, which were found to be involved in the canonical Wnt signaling pathway. Mammalian LRP 6 was shown to bind to Wnt 1 and enhance Wnt-induced developmental processes in Xenopus embryos. Mice lacking LRP 6 exhibited developmental defects that are similar to those caused by deficiencies in various Wnt proteins. Recent work also shows that Wnt proteins induce the binding of LRP 5 to Axin, leading to Axin degradation and beta catenin stabilization.

Bioinformatics

Entrez Human
Mouse
Uniprot Human
Product By Gene ID 4041
Alternate Names
  • low-density lipoprotein receptor-related protein 5
  • EVR4
  • low density lipoprotein receptor-related protein 7
  • LRP-5
  • EVR1
  • OPS
  • osteoporosis pseudoglioma syndrome
  • HBM
  • LRP7exudative vitreoretinopathy 1
  • LR3VBCH2
  • BMND1OPTA1
  • OPPG
  • low density lipoprotein receptor-related protein 5

Research Areas for LRP5/6

Find related products by research area and learn more about each of the different research areas below.

Cell Cycle and Replication
Stem Cell Signaling Pathway
Vision
Wnt Signaling Pathway

Bioinformatics Tool for LRP5/6

Discover related pathways, diseases and genes to LRP5/6. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
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