LPCAT3 Products

Description

Acyltransferase which mediates the conversion of lysophosphatidylcholine (1-acyl-sn-glycero-3-phosphocholine or LPC) into phosphatidylcholine (1,2-diacyl-sn-glycero-3-phosphocholine or PC) (LPCAT activity). Catalyzes also the conversion of lysophosphatidylserine (1-acyl-2-hydroxy-sn-glycero-3-phospho-L-serine or LPS) into phosphatidylserine (1,2-diacyl-sn-glycero-3-phospho-L-serine or PS) (LPSAT activity). Has also weak lysophosphatidylethanolamine acyltransferase activity (LPEAT activity). Favors polyunsaturated fatty acyl-CoAs as acyl donors compared to saturated fatty acyl-CoAs. Seems to be the major enzyme contributing to LPCAT activity in the liver. Lysophospholipid acyltransferases (LPLATs) catalyze the reacylation step of the phospholipid remodeling pathway also known as the Lands cycle

Bioinformatics

Entrez	10162 Human
Uniprot	NP_005759 Human NP_005759.4 Human
Product By Gene ID	10162
Alternate Names	1-acylglycerophosphocholine O-acyltransferase 1-acylglycerophosphoserine O-acyltransferase C3F EC 2.3.1.- EC 2.3.1.23 EC 2.3.1.n6 LPCAT LPLAT 5 Lyso-PC acyltransferase 3 Lyso-PC acyltransferase lysophosphatidylcholine acyltransferase 3LPSAT Lysophosphatidylcholine acyltransferase Lysophosphatidylserine acyltransferase lysophospholipid acyltransferase 5 Lyso-PS acyltransferase MBOAT5OACT5 membrane bound O-acyltransferase domain containing 5 Membrane-bound O-acyltransferase domain-containing protein 5 NESSY nessy O-acyltransferase (membrane bound) domain containing 5 O-acyltransferase domain-containing protein 5 putative protein similar to nessy