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Lactate Dehydrogenase A Inhibitor Screening Products


Description

The human oxidoreductase Lactate Dehydrogenase A (LDHA) (EC:1.1.1.27) is a key enzyme in lactic acid metabolism. It interconverts pyruvate and NADH to lactate and NAD+ respectively. In mammals, LDHA exists as a tetramer and is primarily found in skeletal muscle tissues. LDHA is a common marker to screen for tissue damage and is also known to promote tumor proliferation in breast, lung, and pancreatic cancer patients.