Kv1.6 Products


Potassium channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. Four sequence-related potassium channel genes - shaker, shaw, shab, and shal - have been identified in Drosophila, and each has been shown to have human homologs. This protein is a member of the potassium channel, voltage-gated, shaker-related subfamily. Kv1.6 contains six membrane-spanning domains with a shaker-type repeat in the fourth segment. It belongs to the delayed rectifier class. The coding region of this gene is intronless, and the gene is clustered with genes KCNA1 and KCNA5 on chromosome 12. Kv1.6 is a homologue of the Drosophila gene Shaker, which is involved in reduced sleep and life expectancy.


Entrez Human
Uniprot Human
Product By Gene ID 3742
Alternate Names
  • voltage-gated potassium channel protein Kv1.6
  • Kv1.6
  • potassium voltage-gated channel subfamily A member 6
  • Voltage-gated potassium channel subunit Kv1.6
  • human brain potassium channel-2
  • Voltage-gated potassium channel HBK2
  • KV1.6
  • HBK2
  • FLJ25134
  • potassium voltage-gated channel, shaker-related subfamily, member 6

Pathways for Kv1.6

View related products by pathway and learn more about each of the pathways below.

Signal Transmission

PTMs for Kv1.6

Learn more about PTMs related to Kv1.6.


Bioinformatics Tool for Kv1.6

Discover related pathways, diseases and genes to Kv1.6. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
Vizit™, under license from BioVista Inc.