KDELR2 Products

Antibodies
KDELR2 Antibody
KDELR2 Antibody
NBP1-83982
Species: Hu
Applications: IHC, IHC-P
Host: Rabbit Polyclonal
KDELR2 Antibody
KDELR2 Antibody
H00011014-D01P
Species: Hu
Applications: WB, ELISA
Host: Rabbit Polyclonal
Lysates
KDELR2 Overexpression Lysate ...
KDELR2 Overexpression Lysate (Native)
NBL1-12221
Applications: WB
KDELR2 Overexpression Lysate ...
KDELR2 Overexpression Lysate (Dena...
H00011014-T02
Applications: WB
Proteins
KDELR2 Recombinant Protein
KDELR2 Recombinant Protein
H00011014-P01
Species: Hu
Applications: WB, ELISA, PA
KDELR2 Recombinant Protein An ...
KDELR2 Recombinant Protein Antigen
NBP1-83982PEP
Species: Hu
Applications: AC
RNAi
KDELR2 RNAi
KDELR2 RNAi
H00011014-R02
Species: Hu
Applications: RNAi, RNAi SP

Description

Retention of resident soluble proteins in the lumen of the endoplasmic reticulum (ER) is achieved in both yeast and animal cells by their continual retrieval from the cis-Golgi, or a pre-Golgi compartment. Sorting of these proteins is dependent on a C-terminal tetrapeptide signal, usually lys-asp-glu-leu (KDEL) in animal cells, and his-asp-glu-leu (HDEL) in S. cerevisiae. This process is mediated by a receptor that recognizes, and binds the tetrapeptide-containing protein, and returns it to the ER. In yeast, the sorting receptor encoded by a single gene, ERD2, which is a seven-transmembrane protein. Unlike yeast, several human homologs of the ERD2 gene, constituting the KDEL receptor gene family, have been described. The protein encoded by this gene was the first member of the family to be identified, and it encodes a protein structurally and functionally similar to the yeast ERD2 gene product.

Bioinformatics

Entrez Human
Uniprot Human
Human
Human
Product By Gene ID 11014
Alternate Names
  • ERD-2-like protein
  • KDEL endoplasmic reticulum protein retention receptor 2
  • ER lumen protein retaining receptor 2
  • ERD2-like protein 1
  • ERD2.2FLJ45532
  • ELP-1(Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 2
  • KDEL receptor 2
  • KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 2

Diseases related to KDELR2

Discover more about diseases related to KDELR2.

Hepatitis
Hepatitis C

Bioinformatics Tool for KDELR2

Discover related pathways, diseases and genes to KDELR2. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
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