KCNJ13 Products

KCNJ13 Antibody
KCNJ13 Antibody
Species: Hu
Applications: IHC
Host: Rabbit Polyclonal
KCNJ13 Overexpression Lysate ...
KCNJ13 Overexpression Lysate (Native)
Applications: WB
Species: Hu


FUNCTION: Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it. Their voltage dependence is regulated by the concentration of extracellular potassium; as external potassium is raised, the voltage range of the channel opening shifts to more positive voltages. The inward rectification is mainly due to the blockage of outward current by internal magnesium. KCNJ13 has a very low single channel conductance, low sensitivity to block by external barium and cesium, and no dependence of its inward rectification properties on the internal blocking particle magnesium.; Tissue specificity: Predominantly expressed in small intestine. Expression is also detected in stomach, kidney, and all central nervous system regions tested with the exception of spinal cord.; Subcellular location: Membrane, Multi-pass membrane protein.; Involvement in disease: Defects in KCNJ13 are the cause of snowflake vitreoretinal degeneration (SVD). SVD is a developmental and progressive hereditary eye disorder that affects multiple tissues within the eye. Diagnostic features of SVD include fibrillar degeneration of the vitreous humor, early-onset cataract, minute crystalline deposits in the neurosensory retina, and retinal detachment.


Entrez Human
Uniprot Human
Product By Gene ID 3769
Alternate Names
  • inwardly rectifying subfamily J member 13
  • Inward rectifier K(+) channel Kir7.1
  • MGC33328
  • potassium inwardly-rectifying channel, subfamily J, member 13

Research Areas for KCNJ13

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Bioinformatics Tool for KCNJ13

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