Species: Hu, Mu, Rt
Applications: WB, IHC, IP
Host: Rabbit Monoclonal
Species: Hu, Mu
Applications: WB
Host: Mouse Monoclonal
Species: Hu, Mu
Applications: WB
Host: Goat Polyclonal
Species: Hu
Applications: WB
Species: Hu
Applications: AC
Description
The activator protein-1 (AP-1) transcription factor consists of either Jun/Jun homodimers or Fos/Jun heterodimeric complexes. Homo- and heterodimers bind to the TGACTCA consensus sequence present in numerous promoters and initially identified as the phorbol ester tumor promoter response element (TRE). Jun B and Jun D have been shown to be almost identical to c-Jun in their C-terminal regions, which are involved in dimerization and DNA binding, whereas their N-terminal domains, which are involved in transcriptional activation, diverge. All three form heterodimers among themselves and with c-Fos and other members of the Fos gene family. Studies suggest that the two forms of Jun D may be due to internal initiation of translation.
Bioinformatics
| Entrez |
Mouse
Rat
Human
|
| Uniprot |
Human
Human
|
| Product By Gene ID |
3727 |
| Alternate Names |
- activator protein 1
- AP-1
- jun D proto-oncogene
- JunD-FL isoform
- transcription factor jun-D
|
Research Areas for JunD
Find related products by research area and learn more about each of the different research areas below.
Phospho-Specific
