IL-7 R alpha/CD127 Products

Antibodies
IL-7 R alpha/CD127 Antibody ( ...
IL-7 R alpha/CD127 Antibody (1140A...
MAB7473
Species: Mu
Applications: Flow
Host: Rabbit Monoclonal
Conjugate Catalog # Availability Size Price
Antibody Pairs
IL-7 R alpha/CD127 Antibody P ...
IL-7 R alpha/CD127 Antibody Pair
H00003575-AP21
Species: Hu
Applications: S-ELISA
Lysates
IL-7 R alpha/CD127 Overexpres ...
IL-7 R alpha/CD127 Overexpression ...
H00003575-T01
Species: Hu
Applications: WB
IL-7 R alpha/CD127 Overexpres ...
IL-7 R alpha/CD127 Overexpression ...
NBL1-11966
Applications: WB
Proteins
IL-7 R alpha/CD127 Recombinan ...
IL-7 R alpha/CD127 Recombinant Pro...
H00003575-P01
Species: Hu
Applications: WB, ELISA, PA
IL-7 R alpha/CD127 Recombinan ...
IL-7 R alpha/CD127 Recombinant Pro...
H00003575-G01
Species: Hu
RNAi
IL-7 R alpha/CD127 RNAi
IL-7 R alpha/CD127 RNAi
H00003575-R02
Species: Hu

Description

Interleukin-7 is a glycoprotein involved in the regulation of lymphopoiesis. Response of cells to IL7 is dependent on the presence of the interleukin 7 receptor (IL7R); the active receptor is an alpha/gamma chain heterodimer. The gamma(c) chain, which also associates with the interleukin-2 receptor, serves primarily to activate signal transduction by the IL7R complex, while the alpha chain of IL7R determines specific signaling events through its association with cytoplasmic signaling molecules. The human and mouse sequence is nearly identical. In humans, severe combined immunodeficiency is caused by genetic defects in IL-7 receptor. The tyrosine residue at the 449 position is a critical signaling site of the intracellular domain of IL-7 receptor. This site is rapidly phosphorylated by janus kinases after the IL-7 receptor is engaged.

Bioinformatics

Entrez Human
Mouse
Rat
Uniprot Human
Human
Human
Human
Human
Human
Mouse
Product By Gene ID 3575
Alternate Names
  • IL7RA
  • CDw127
  • IL-7R subunit alpha
  • interleukin-7 receptor subunit alpha
  • IL-7 receptor subunit alpha
  • interleukin 7 receptor isoform H5-6
  • CD127 antigen
  • interleukin 7 receptor alpha chain
  • IL-7RA
  • IL-7R-alpha
  • CD127ILRA
  • CDW127
  • interleukin 7 receptor

Research Areas for IL-7 R alpha/CD127

Find related products by research area and learn more about each of the different research areas below.

Apoptosis
Cytokine Research
Immunology
Innate Immunity
Phospho-Specific

PTMs for IL-7 R alpha/CD127

Learn more about PTMs related to IL-7 R alpha/CD127.

Phosphorylation
Cleavage

Bioinformatics Tool for IL-7 R alpha/CD127

Discover related pathways, diseases and genes to IL-7 R alpha/CD127. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
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