IL-3 R alpha/CD123 Products

Antibodies
Lysates
IL-3 R alpha/CD123 Overexpres ...
IL-3 R alpha/CD123 Overexpression ...
NBL1-11956
Applications: WB
IL-3 R alpha/CD123 Overexpres ...
IL-3 R alpha/CD123 Overexpression ...
H00003563-T01
Species: Hu
Applications: WB
Proteins
Recombinant Human IL-3 R alph ...
Recombinant Human IL-3 R alpha/CD1...
301-R3
Species: Hu
Applications: Bind
Recombinant Mouse IL-3 R alph ...
Recombinant Mouse IL-3 R alpha/CD1...
983-MR
Species: Mu
Applications: BA
IL-3 R alpha/CD123 Recombinan ...
IL-3 R alpha/CD123 Recombinant Pro...
NBP1-86549PEP
Species: Hu
Applications: AC
RNAi
IL-3 R alpha/CD123 RNAi
IL-3 R alpha/CD123 RNAi
H00003563-R02
Species: Hu
Applications: RNAi, RNAi SP

Description

IL3RA (CD123) is a member of the immunoglobulin superfamily that is expressed on hematopoietic progenitors, basophils, mast cells, and megakaryocytes. This transmembrane glycoprotein can bind IL3 with low affinity but cannot transduce signals without association with additional protein partners. CD123 can complex with either common beta chain (CDw131) or the IL3RB chain to form high affinity heterodimeric IL3 receptors. CDw131 can complex with the Alpha subunits of the mouse IL3R, IL5R and GMCSFR to form high affinity receptors, while the IL3RB subunit is specific for IL3 but binds with low affinity. IL3 binding to the receptor complex can induce proliferation and differentiation of hematopoietic cells. It is present in Hematopoietic progenitors, basophils, mast cells and megakaryocytes.

Bioinformatics

Entrez Human
Mouse
Uniprot Human
Human
Human
Human
Product By Gene ID 3563
Alternate Names
  • hIL3Ra
  • interleukin-3 receptor subunit alpha
  • IL-3 receptor subunit alpha
  • hIL-3Ra
  • CD123 antigen
  • MGC34174
  • IL3R
  • IL3RY
  • IL-3RA
  • IL3RX
  • IL-3R-alpha
  • IL3RAY
  • CD123
  • IL-3R subunit alpha
  • interleukin 3 receptor, alpha (low affinity)

Research Areas for IL-3 R alpha/CD123

Find related products by research area and learn more about each of the different research areas below.

Cytokine Research
Phospho-Specific

PTMs for IL-3 R alpha/CD123

Learn more about PTMs related to IL-3 R alpha/CD123.

Phosphorylation
Methylation
Acetylation

Bioinformatics Tool for IL-3 R alpha/CD123

Discover related pathways, diseases and genes to IL-3 R alpha/CD123. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
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