IgL Products

Antibodies
IgL Antibody (Lamb14)
IgL Antibody (Lamb14)
NBP2-45078
Species: Hu
Applications: WB, Flow, IHC-P, IF
Host: Mouse Monoclonal
Formulation Catalog # Availability Price  
IgL Antibody
IgL Antibody
H00003535-B01P
Species: Hu
Applications: WB, ELISA
Host: Mouse Polyclonal
Lysates
IgL Overexpression Lysate (De ...
IgL Overexpression Lysate (Denatured)
H00003535-T02
Applications: WB
IgL Overexpression Lysate (De ...
IgL Overexpression Lysate (Denatured)
H00003535-T01
Applications: WB
Proteins
IgL Recombinant Protein
IgL Recombinant Protein
H00003535-P01
Species: Hu
Applications: WB, ELISA, PA

Description

Immunoglobulins recognize foreign antigens and initiate immune responses such as phagocytosis and the complement system. Each immunoglobulin molecule consists of two identical heavy chains and two identical light chains. There are two classes of light chains, kappa and lambda. This region represents the germline organization of the lambda light chain locus. The locus includes V (variable), J (joining), and C (constant) segments. During B cell development, a recombination event at the DNA level joins a single V segment with a J segment; the C segment is later joined by splicing at the RNA level. Recombination of many different V segments with several J segments provides a wide range of antigen recognition. Additional diversity is attained by junctional diversity, resulting from the random additional of nucleotides by terminal deoxynucleotidyltransferase, and by somatic hypermutation, which occurs during B cell maturation in the spleen and lymph nodes. Several V segments and three C segments are known to be incapable of encoding a protein and are considered pseudogenes. The locus also includes several non-immunoglobulin genes, many of which are pseudogenes or are predicted by automated computational analysis or homology to other species. [provided by RefSeq]

Bioinformatics

Entrez Human
Uniprot Human
Human
Product By Gene ID 3535
Alternate Names
  • Lambda Light Chain
  • immunoglobulin lambda gene cluster
  • ig lambda-6 chain C region
  • MGC88804
  • IGLC6
  • IGL
  • immunoglobulin lambda locus

Pathways for IgL

View related products by pathway and learn more about each of the pathways below.

Translation
Meiosis

Bioinformatics Tool for IgL

Discover related pathways, diseases and genes to IgL. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
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