I-Ak Products


Description

The 10-3.6 antibody reacts with the beta chain of the I-Ak MHC class II alloantigen. This class II molecule is expressed on antigen presenting cells (including B cells) and a subset of T cells from H-2k bearing mice and involved in antigen presentation to T cells expressing CD3/TCR and CD4 proteins. The 10-3.6 antibody cross-reacts with I-Af,r,s antigens; does not react with other haplotypes (e.g., b, d, p, q).

Bioinformatics

Alternate Names
  • MHC class II Ak
  • MHC class II Ak
  • MHC class II Ak
  • MHC class II Ak
  • MHC class II Ak
  • MHC class II Ak