HSV gG-2 Products


Herpes simplex type 2 (HSV-2) belongs to a family that includes HSV-1, Epstein-Barr virus (EBV) and Varicella zoster (chicken pox) virus. HSV-1 and HSV-2 are extremely difficult to distinguish from each other. These viruses have a DNA genome, an icosahedral protein coat and are encased in a lipid membrane derived from the nuclear membrane of the last host. These viruses are capable of entering a latent phase where the host shows no visible sign of infection and levels of infectious agent become very low. During the latent phase the viral DNA is integrated into the genome of the host cell. Glycoprotein B (gB) is the most highly conserved envelope glycoprotein of herpesviruses. The gB protein is required for virus infectivity and cell penetration. Recombinant forms of gB being used for the development of subunit vaccines are able to induce virus-neutralizing antibodies and protective efficacy in animal models.


Alternate Names
  • gB
  • UL27 glycoprotein B
  • UL27
  • HSV2 UL27
  • HSV2 glycoprotein B
  • Glycoprotein B