HOXA13 Products

Description

HOXA13 is 388 amino acids long, weighing approximately 40 kDa, that functions as a sequence-specific transcription factor which focuses on the specific positional identities of cells on the anterior-posterior axis, which is all part of a developmental regulatory system. Current studies are being done on several diseases and disorders including triphalangeal thumbs brachyectrodactyly, guttmacher syndrome, short stature, hypospadias, esophageal squamous cell carcinoma, labryinthitis, leukemia, ulcerative colitis, Hirschsprung's disease, microphthalmia, and vaginitis.HOXA13 has also been shown to have interactions with MEIS1, SMAD2, MEIS2, MEIS3, and SMAD1.

Bioinformatics

Entrez	3209 Human
Uniprot	NP_000513 Human
Product By Gene ID	3209
Alternate Names	homeo box 1J homeo box A13 homeobox A13 Homeobox protein Hox-1J homeobox protein HOXA13 HOX1 HOX1Jhomeobox protein Hox-A13 transcription factor HOXA13

Diseases related to HOXA13

Discover more about diseases related to HOXA13.

Malignant Neoplasms
Limb Deformities, Congenital
Neoplasms
Congenital Hand Deformities
Congenital Foot Deformity
Leukemia
Hypospadias
Carcinoma
Congenital Abnormality
Urogenital Abnormalities
Polydactyly
Chromosomal Translocation
Leukemia, Myelocytic, Acute
Myeloid Leukemia
Cell Transformation, Neoplastic
Malignant Squamous Cell Neoplasm
Esophageal Neoplasms
Leukemogenesis

Pathways for HOXA13

View related products by pathway and learn more about each of the pathways below.

Limb Development
Cell Proliferation
Regeneration
Limb Morphogenesis
Embryonic Morphogenesis
Ossification
Cell Differentiation
Localization
Dna Replication
Pathogenesis
Inflammatory Response
Translation
Cell Motility
Methylation
Cell Death
Cell Adhesion
Muscle Cell Differentiation
Immune Response
Negative Regulation Of Cell Proliferation
Sex Determination

PTMs for HOXA13

Learn more about PTMs related to HOXA13.

Methylation
Phosphorylation
Acetylation

Bioinformatics Tool for HOXA13

Discover related pathways, diseases and genes to HOXA13. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.