HMG1L10 Products

Description

High mobility group (HMG) proteins 1 and 2 are ubiquitous non-histone components of chromatin. Research suggests that the binding of HMG proteins to DNA induces alterations in the DNA architecture, including DNA bending and unwinding of the helix. HMG proteins synergize with Oct-2, ATF-2, c-Jun and members of the NFkappaB family to activate transcription. Additional studies indicate that phosphorylation of HMG protein is required to stimulate the transcriptional activity of the protein. Human HMG-1 and HMG-2 each contain two DNA-binding domains, termed HMG boxes. HMG proteins bind singlestranded DNA but induce conformational changes in double-stranded DNA alone.

Bioinformatics

Entrez	100130561 Human 25459 Rat
Product By Gene ID	100130561
Alternate Names	HMGB1P10 high mobility group box 1 pseudogene 10 bK445C9.3 HMG1L10 HMGB1L10 bK445C9.3

Research Areas for HMG1L10

Find related products by research area and learn more about each of the different research areas below.

Chromatin Research
Neuroscience

Bioinformatics Tool for HMG1L10

Discover related pathways, diseases and genes to HMG1L10. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.