Description
MHC Class II antigens are heterodimers consisting of one alpha chain(31-34kD) and one beta chain (26-29kD). The family of monoclonal antibodies (ER-TR 3, ER-TR 2, ER-TR 1) detect MHC class II antigens encoded by the murine Ia region of the H-2 complex, corresponding to the human HLA-DR region. MHC Class II antigens are a valuable tool for studying T helper cell interaction with class II positive antigen presenting cells (dendritic cells, B cells, macrophages) and offer new possibilities for studying the development of T helper cells since these antibodies also stain stromal cells in the thymus. MHC Class II antigens are also inducible on a number of other cells (endothelium and epithelial cells) by interferon gamma.
Bioinformatics
| Product By Gene ID |
3117 |
| Alternate Names |
- CD
- CELIAC1DQ alpha 1 chain
- DC-1 alpha chain
- DQ-A1
- FLJ27088
- FLJ27328
- GSE
- HLA class II histocompatibility antigen, DQ(W3) alpha chain
- HLA-DCA
- HLA-DQA
- leucocyte antigen DQA1
- leukocyte antigen alpha chain
- major histocompatibility complex, class II, DQ alpha 1
- MGC149527
- MHC class II antigen
- MHC class II DQA1
- MHC class II HLA-D alpha glycoprotein
- MHC class II HLA-DQ-alpha-1
- MHC class II surface glycoprotein
- MHC HLA-DQ alpha
|
Research Areas for HLA DQ/DR
Find related products by research area and learn more about each of the different research areas below.
Adaptive ImmunityAsthmaImmunology
