Histone H3T Products


Changes in chromatin structure play a large role in the regulation of transcription in eukaryotes (1). The nucleosome is the primary building block of chromatin, and is made up of four core histone proteins (H2A, H2B, H3 and H4) (2). Acetylation of core histones regulates gene expression (2). Histone H3 is primarily acetylated at lysines 9, 14, 18, and 23 (3,4). Acetylation at lysine 9 appears to have a dominant role in histone deposition and chromatin assembly in some organisms (3,4).. H3t (H.34) differs from the consensus mammalian H3 structure by four amino acid residues and it is mainly expressed in testicular cells. H3t encoding gene maps to chromosome 1 (1q42), unlike the majority of the human histone genes that form cluster on chromosome 6 and outside of replication-dependent H3 genes (5).


Entrez Human
Uniprot Human
Product By Gene ID 8290
Alternate Names
  • H3FT
  • H3/g
  • H3.4
  • H3t
  • histone cluster 3, H3
  • HIST3H3

Diseases related to Histone H3T

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Malignant Neoplasms
Metaplastic Cell Transformation
Malignant Tumor Of Cervix

Pathways for Histone H3T

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Rna Surveillance
Immune Response

Bioinformatics Tool for Histone H3T

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Related Histone H3T Blog Posts

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H3.1t - A testis-specific histone variant
Histones are nuclear proteins essential for the storage and organization of genomic DNA as chromatin. Chromatin consists of DNA wrapped tightly around histone oligomers to form nucleosomes. In addition to compacting the genome, histones also regula...    Read more.
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