Species: Hu
Applications: WB
Description
Histones are nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber as they play a critical role in transcription regulation, DNA repair, DNA replication, and chromosomal stability. The intronless HIST1H3G gene is found on chromosome 6 and encodes a 136 amino acid long, 15 kDA protein that lacks a polyA tail but instead contains palindromic termination elements. It is involved with the interferon pathway, PKA signaling, meiosis, amyloids, hemostasis, and UVB-induced MAPK signaling. HIST1H3g is known to interact with genes AIRE, HIST1H4A, HIST1H4B, HIST1H4C, and CCDC101. Researchers have investigated its role in lupus and immunodeficiency.
Bioinformatics
Entrez |
Human |
Uniprot |
Human |
Product By Gene ID |
8355 |
Alternate Names |
- H3 histone family, member H
- H3/h
- H3FA
- H3FB
- H3FC
- H3FD
- H3FF
- H3FHHIST1H3D
- H3FI
- H3FJ
- H3FK
- H3FL
- HIST1H3A
- HIST1H3B
- HIST1H3C
- HIST1H3E
- HIST1H3F
- HIST1H3H
- HIST1H3I
- HIST1H3J
- histone 1, H3g
- histone cluster 1, H3g
- histone H3.1
- Histone H3/a
- Histone H3/b
- Histone H3/c
- Histone H3/d
- Histone H3/f
- Histone H3/h
- Histone H3/i
- Histone H3/j
- Histone H3/k
- Histone H3/l
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