HIRA Products

Antibodies
HIRA Antibody
HIRA Antibody
H00007290-B01P
Species: Hu
Applications: WB, ICC/IF
Host: Mouse Polyclonal
HIRA Antibody
HIRA Antibody
NBP2-38636
Species: Hu, Mu, Rt
Applications: IHC, IHC-P
Host: Rabbit Polyclonal
HIRA Antibody
HIRA Antibody
NBP2-55647
Species: Hu, Mu, Rt
Applications: ICC/IF
Host: Rabbit Polyclonal
Lysates
HIRA Overexpression Lysate (D ...
HIRA Overexpression Lysate (Denatu...
H00007290-T01
Species: Hu
Applications: WB
Proteins
Recombinant Human HIRA Protei ...
Recombinant Human HIRA Protein
H00007290-P01
Species: Hu
Applications: WB, ELISA, PA
Recombinant Human HIRA Protei ...
Recombinant Human HIRA Protein
H00007290-Q01
Species: Hu
Applications: WB, ELISA, PA
HIRA Recombinant Protein Anti ...
HIRA Recombinant Protein Antigen
NBP2-55647PEP
Species: Hu
Applications: AC
RNAi
HIRA RNAi
HIRA RNAi
H00007290-R01
Species: Hu
Applications: RNAi, RNAi SP

Description

HIRA encodes a histone chaperone that preferentially places the variant histone H3.3 in nucleosomes. Orthologs of this gene in yeast, flies, and plants are necessary for the formation of transcriptionally silent heterochomatin. This gene plays an important role in the formation of the senescence-associated heterochromatin foci. These foci likely mediate the irreversible cell cycle changes that occur in senescent cells. It is considered the primary candidate gene in some haploinsufficiency syndromes such as DiGeorge syndrome, and insufficient production of the gene may disrupt normal embryonic development. [provided by RefSeq]

Bioinformatics

Entrez Human
Uniprot Human
Human
Human
Human
Product By Gene ID 7290
Alternate Names
  • TUP1-like enhancer of split protein 1
  • HIR
  • TUP1
  • TUPLE1protein HIRA
  • DGCR1DiGeorge critical region gene 1
  • HIR (histone cell cycle regulation defective) homolog A (S. cerevisiae)
  • HIR histone cell cycle regulation defective homolog A (S. cerevisiae)

Bioinformatics Tool for HIRA

Discover related pathways, diseases and genes to HIRA. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
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