Hepatitis B Virus Products

Antibodies
Hepatitis B Virus Antibody
Hepatitis B Virus Antibody
NB100-66430
Species: Vi
Applications: WB, ELISA
Host: Rabbit Polyclonal
ELISA Kits

Description

Hepatitis B Virus (HBV) infection induces a disease state characterized by liver damage, inflammation and viral persistence. Infection also increases the risk of hepatocellular carcinoma. HBV belongs to the Hepadnaviridae family of viruses. Its genome consists of partially double stranded circular DNA. The DNA is enclosed in a nucleocapsid, or core antigen (HBcAg), which is surrounded by a spherical envelope (surface antigen or HBsAg). The core antigen shares its sequences with the e antigen (HBeAg) but no cross reactivity between the two proteins has been observed. The HBV genome also encodes a DNA polymerase that also acts as a reverse transcriptase. Hepatitis B infection is normally diagnosed from serological tests that detect HBsAg but as the disease progresses this antigen may no longer be present in the blood and tests for HBcAg are used. If HBsAg can be detected in the blood for longer than six months, chronic hepatitis B is diagnosed. The antigenic determinant of the protein moiety of the HBsAg determines specific characteristics of different serotypes and provides the basis of immunodetection. HBsAg has antigenic heterogeneity, specifically, two pairs of sub specific determinants, d/y and w/r allow the following combinations: adw, ayw, adr, ayr.

Bioinformatics

Alternate Names
  • Hepatitis B Receptor Binding Fragment Pre S
  • HBsAg

Research Areas for Hepatitis B Virus

Find related products by research area and learn more about each of the different research areas below.

Virology, Bacteria and Parasites