HARS2 Products

HARS2 Overexpression Lysate
HARS2 Overexpression Lysate
Species: Hu
Applications: WB
Recombinant Human HARS2 GST ( ...
Recombinant Human HARS2 GST (N-Ter...
Species: Hu
Applications: WB, ELISA, PA, AP
HARS2 Recombinant Protein Ant ...
HARS2 Recombinant Protein Antigen
Species: Hu
Applications: AC


The HARS2 gene encodes a 506 amino acid, 56kDA probable histidine--tRNA ligase (mitochondrial) protein that is member to the II family of aminoacyl-tRNA synthetases which charge tRNA with cognate amino acids. The HARS2 gene is located in a head-to-head orientation with HARS on chromosome 5, which is the location of where homologous genes share a bidirectional promoter. The protein works as an accessory in the regulation of protein biosynthesis through the synthesis of histidyl-transfer RNA. HARS2 is involved in gene expression and mitochondrian tRNA aminoacylation and has been known to interact with genes ICT1, AARS2, AASS, ABSB7, and ACAD9. HARS2 has been investigated in immunodeficiency, malaria, pneumonia, hearing loss, tuberculosis, schizophrenia, and ovarian dysgenesis.


Entrez Human
Uniprot Human
Product By Gene ID 23438
Alternate Names
  • hisRS
  • EC 6.1.1
  • Histidine--tRNA ligase-like
  • HARS-related
  • Histidine--tRNA ligase
  • histidyl-tRNA synthetase-like
  • HisRS
  • EC
  • HARSLprobable histidyl-tRNA synthetase, mitochondrial
  • HO3histidine-tRNA ligase homolog
  • HARSRhistidine tRNA ligase 2, mitochondrial (putative)
  • histidine translase
  • histidyl-tRNA synthetase 2, mitochondrial (putative)

Pathways for HARS2

View related products by pathway and learn more about each of the pathways below.

Mitochondrial Translation

Bioinformatics Tool for HARS2

Discover related pathways, diseases and genes to HARS2. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
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