GUCY2D Products

Description

GUCY2D encodes a retina-specific guanylate cyclase, which is a member of the membrane guanylyl cyclase family. Like other membrane guanylyl cyclases, this enzyme has a hydrophobic amino-terminal signal sequence followed by a large extracellular domain, a single membrane spanning domain, a kinase homology domain, and a guanylyl cyclase catalytic domain. In contrast to other membrane guanylyl cyclases, this enzyme is not activated by natriuretic peptides. Mutations in this gene result in Leber congenital amaurosis and cone-rod dystrophy-6 diseases. [provided by RefSeq]

Bioinformatics

Entrez	3000 Human
Uniprot	NP_000171 Human
Product By Gene ID	3000
Alternate Names	EC 4.6.1 GUC1A4 RETGC1 Rod outer segment membrane guanylate cyclase RETGC Guanylate cyclase 2D, retinal retinal guanylyl cyclase 1 retGC ROSGC ROS-GC1 LCA CYGD GUC2DCORD5 CORD6cone rod dystrophy 5/6 LCA1RCD2 RETGC-1EC 4.6.1.2 ROS-GC guanylate cyclase 2D, membrane (retina-specific)

Diseases related to GUCY2D

Discover more about diseases related to GUCY2D.

Amaurosis
Leber Congenital Amaurosis
Dystrophy
Blind Vision
Retinitis Pigmentosa
Retinal Degeneration
Retinal Dystrophies
Retinal Diseases
Visual Impairment
Optic Atrophy, Hereditary, Leber
Atrophy
Optic Atrophies, Hereditary
Macule
Color Vision Defect
Nystagmus
Night Blindness
Age Related Macular Degeneration
Disorder Of Eye
Blindness Congenital

Pathways for GUCY2D

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Phototransduction
Transport
Visual Behavior
Localization
Synaptic Transmission
Associative Learning
Nuclear Transport
Translation
Phagocytosis
Cell Death
Water Homeostasis
Optomotor Response
Hatching
Mating
Segmentation
Pathogenesis
Rna Interference

Research Areas for GUCY2D

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Protein Kinase

Bioinformatics Tool for GUCY2D

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