Species: Hu, Mu, Rt
Applications: WB, ELISA, ICC/IF, IHC
Host: Rabbit Polyclonal
Species: Hu
Applications: WB, ELISA, ICC/IF
Host: Mouse Monoclonal
Species: Hu
Applications: WB, ELISA, ICC/IF
Host: Mouse Monoclonal
Species: Hu
Applications: WB
Description
GUCY2D encodes a retina-specific guanylate cyclase, which is a member of the membrane guanylyl cyclase family. Like other membrane guanylyl cyclases, this enzyme has a hydrophobic amino-terminal signal sequence followed by a large extracellular domain, a single membrane spanning domain, a kinase homology domain, and a guanylyl cyclase catalytic domain. In contrast to other membrane guanylyl cyclases, this enzyme is not activated by natriuretic peptides. Mutations in this gene result in Leber congenital amaurosis and cone-rod dystrophy-6 diseases. [provided by RefSeq]
Bioinformatics
| Entrez |
Human
|
| Uniprot |
Human
|
| Product By Gene ID |
3000 |
| Alternate Names |
- CORD6cone rod dystrophy 5/6
- CYGD
- EC 4.6.1
- guanylate cyclase 2D, membrane (retina-specific)
- Guanylate cyclase 2D, retinal
- GUC1A4
- GUC2DCORD5
- LCA
- LCA1RCD2
- RETGC
- retGC
- RETGC1
- RETGC-1EC 4.6.1.2
- retinal guanylyl cyclase 1
- Rod outer segment membrane guanylate cyclase
- ROSGC
- ROS-GC
- ROS-GC1
|
Research Areas for GUCY2D
Find related products by research area and learn more about each of the different research areas below.
Protein Kinase
