GRK4 Products

Antibodies
GRK4 Antibody (6D12)
GRK4 Antibody (6D12)
H00002868-M01
Species: Hu
Applications: WB, ELISA, ICC/IF
Host: Mouse Monoclonal
GRK4 Antibody
GRK4 Antibody
NBP2-37960
Species: Hu
Applications: IHC, IHC-P
Host: Rabbit Polyclonal
GRK4 Antibody (4F5)
GRK4 Antibody (4F5)
NBP2-45914
Species: Hu
Applications: WB
Host: Mouse monoclonal
Lysates
GRK4 Overexpression Lysate (N ...
GRK4 Overexpression Lysate (Native)
NBP2-04793
Applications: WB
Proteins
GRK4 Partial Recombinant Prot ...
GRK4 Partial Recombinant Protein
H00002868-Q01
Species: Hu
Applications: WB, ELISA, PA
GRK4 Recombinant Protein Anti ...
GRK4 Recombinant Protein Antigen
NBP2-37960PEP
Species: Hu
Applications: AC
RNAi
GRK4 RNAi
GRK4 RNAi
H00002868-R05
Species: Hu
GRK4 RNAi
GRK4 RNAi
H00002868-R06
Species: Hu
GRK4 RNAi
GRK4 RNAi
H00002868-R08
Species: Hu

Description

A guanine nucleotide-binding protein (G Protein)-coupled receptor kinase subfamily, of the Ser/Thr protein kinase family, is encoded by the gene GRK4. There are a total of four isoforms of this gene: GRK4-alpha is 578 amino acids long at 66 kDA; GRK4-beta is 546 amino acids long at 63 kDA; GRK4-delta is 500 amino acids long at 57 kDA; and isoform 4, GRK4-gamma is 532 amino acids long at 61 kDA. GRK4-alpha is inhibited by caulmodulin and can phosphorylate rhodopsin, however the three other forms of GRK4 do not interact with calmodulin. GRK4 has been investigated in hypertension, breast cancer, aortic coarctation, and atherosclerosis. It participates in endocytosis and the chemokine signaling pathway through interactions with the CALM1, CALM2, CALM3, FSHR, and IKBKG genes.

Bioinformatics

Entrez Human
Uniprot Human
Human
Product By Gene ID 2868
Alternate Names
  • EC 2.7.11
  • EC 2.7.11.16
  • G-protein coupled receptor kinase 4
  • ITI1
  • G protein-coupled receptor kinase GRK4
  • GPRK2LIT11
  • GPRK4GRK4a
  • G protein-coupled receptor kinase 2-like (Drosophila)
  • G protein-coupled receptor kinase 4

Research Areas for GRK4

Find related products by research area and learn more about each of the different research areas below.

Protein Kinase

PTMs for GRK4

Learn more about PTMs related to GRK4.

Phosphorylation
Palmitoylation
Prenylation
Methylation

Bioinformatics Tool for GRK4

Discover related pathways, diseases and genes to GRK4. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
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