Glucocorticoid Receptor beta Products

Description

The protein encoded by this gene is a receptor for glucocorticoids that can act as both a transcription factor and as a regulator of other transcription factors. This protein can also be found in heteromeric cytoplasmic complexes along with heat shock factors and immunophilins. The protein is typically found in the cytoplasm until it binds a ligand, which induces transport into the nucleus. Mutations in this gene are a cause of glucocorticoid resistance, or cortisol, resistance. Alternate splicing, the use of at least three different promoters, and alternate translation initiation sites result in several transcript variants encoding the same protein or different isoforms, but the full-length nature of some variants has not been determined. [provided by RefSeq]

Bioinformatics

Uniprot	P04150
Product By Gene ID	2908
Alternate Names	GCR glucocorticoid receptor GRGCCR GRLNuclear receptor subfamily 3 group C member 1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) nuclear receptor subfamily 3, group C, member 1

Research Areas for Glucocorticoid Receptor beta

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Signal Transduction