GCNT2 Products

Description

GCNT2 encodes the enzyme responsible for formation of the blood group I antigen. The i and I antigens are distinguished by linear and branched poly-N-acetyllactosaminoglycans, respectively. The encoded protein is the I-branching enzyme, a beta-1,6-N-acetylglucosaminyltransferase responsible for the conversion of fetal i antigen to adult I antigen in erythrocytes during embryonic development. Mutations in this gene have been associated with adult i blood group phenotype. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq]

Bioinformatics

Entrez	2651 Human
Uniprot	NP_663624 Human NP_663630 Human NP_663630.2 Human
Product By Gene ID	2651
Alternate Names	glucosaminyl (N-acetyl) transferase 2, I-branching enzyme EC 2.4.1.150 cataract, congenital N-acetyllactosaminide beta-1,6-N-acetylglucosaminyltransferase I-branching enzyme N-acetyllactosaminide beta-1,6-N-acetylglucosaminyl-transferase NACGT1 Ii blood group N-acetylglucosaminyltransferase I-branching beta-1,6-acetylglucosaminyltransferase II I beta-1,6-N-acetylglucosaminyltransferase GCNT5 beta-1,6-N-acetylglucosaminyltransferase 2 bA421M1.1 MGC163396 bA360O19.2 GCNT2C ULG3 CCAT NAGCT1 IGNTglucosaminyl (N-acetyl) transferase 5 glucosaminyl (N-acetyl) transferase 2, I-branching enzyme (Ii blood group) glucosaminyl (N-acetyl) transferase 2, I-branching enzyme (I blood group)

Diseases related to GCNT2

Discover more about diseases related to GCNT2.

Cataract
Cell Invasion
Neoplasm Metastasis
Lung Neoplasms
Metastatic Malignant Neoplasm To The Lung
Malignant Neoplasm Of Breast
Schizophrenia
Idiopathic Hypereosinophilic Syndrome
Tissue Adhesions
Neoplasm Invasiveness
Diabetes Mellitus
Iron Metabolism Disorders
Autoimmune Reaction
Disorder Of Eye
Malignant Neoplasms
Neoplasms
Diabetes Mellitus, Insulin-dependent
Mammary Neoplasms
Dog Diseases

Pathways for GCNT2

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Gene Conversion
Cell Migration
Glycosylation

PTMs for GCNT2

Learn more about PTMs related to GCNT2.

Glycosylation

Bioinformatics Tool for GCNT2

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