GCNT2 Products

Description

GCNT2 encodes the enzyme responsible for formation of the blood group I antigen. The i and I antigens are distinguished by linear and branched poly-N-acetyllactosaminoglycans, respectively. The encoded protein is the I-branching enzyme, a beta-1,6-N-acetylglucosaminyltransferase responsible for the conversion of fetal i antigen to adult I antigen in erythrocytes during embryonic development. Mutations in this gene have been associated with adult i blood group phenotype. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq]

Bioinformatics

Entrez	2651 Human
Uniprot	NP_663624 Human NP_663630 Human NP_663630.2 Human
Product By Gene ID	2651
Alternate Names	bA360O19.2 bA421M1.1 beta-1,6-N-acetylglucosaminyltransferase 2 cataract, congenital CCAT EC 2.4.1.150 GCNT2C GCNT5 glucosaminyl (N-acetyl) transferase 2, I-branching enzyme (I blood group) glucosaminyl (N-acetyl) transferase 2, I-branching enzyme (Ii blood group) glucosaminyl (N-acetyl) transferase 2, I-branching enzyme I beta-1,6-N-acetylglucosaminyltransferase I-branching beta-1,6-acetylglucosaminyltransferase I-branching enzyme IGNTglucosaminyl (N-acetyl) transferase 5 Ii blood group II MGC163396 N-acetylglucosaminyltransferase N-acetyllactosaminide beta-1,6-N-acetylglucosaminyltransferase N-acetyllactosaminide beta-1,6-N-acetylglucosaminyl-transferase NACGT1 NAGCT1 ULG3