GATA2/3 Products

GATA2/3 Antibody
GATA2/3 Antibody
Species: Hu, Mu
Applications: ICC/IF, IHC, IHC-P
Host: Rabbit Polyclonal


The genes for all 4 subunits of the T-cell antigen receptor (alpha, beta, gamma and delta) are controlled by distinct enhancers and their enhancer-binding proteins. Marine and Winoto (1991) identified a common TCR regulatory element by demonstrating binding of the enhancer-binding protein GATA3 to the enhancer elements of all 4 TCR genes. GATA3 had been shown in the chicken to be an enhancer-binding protein containing a zinc finger domain. GATA3 mRNA was demonstrated by Northern blot analysis in T cells but not in B cells or macrophages. GATA3 is abundantly expressed in the T-lymphocyte lineage and is thought to participate in T-cell receptor gene activation through binding to enhancers. Labastie et al. (1994) cloned the human gene and the 5-prime end of the mouse gene. The human gene comprises 6 exons distributed over 17 kb of DNA. Its 2 zinc fingers are encoded by 2 separate exons highly conserved with those of GATA1, but no other structural homologies between the 2 genes could be found.


Entrez Human
Product By Gene ID 2624
Alternate Names
  • FLJ45948
  • endothelial transcription factor GATA-2
  • GATA-binding protein 2NFE1B
  • MGC2306
  • GATA binding protein 2

Bioinformatics Tool for GATA2/3

Discover related pathways, diseases and genes to GATA2/3. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
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