Gastrin Products

Antibodies
Gastrin Antibody
Gastrin Antibody
33280002
Species: Hu
Applications: ELISA
Host: Rabbit Polyclonal
Gastrin Antibody
Gastrin Antibody
NBP2-89004
Species: Hu, Rt, Po
Applications: IHC
Host: Rabbit Polyclonal
Gastrin Antibody
Gastrin Antibody
NBP3-02945
Species: Mu
Applications: WB
Host: Rabbit Polyclonal
ELISA Kits
Rat Gastrin ELISA Kit (Colori ...
Rat Gastrin ELISA Kit (Colorimetric)
NBP2-61291
Species: Rt
Applications: ELISA
Human Gastrin ELISA Kit (Colo ...
Human Gastrin ELISA Kit (Colorimet...
NBP2-61305
Species: Hu
Applications: ELISA
Lysates
Gastrin Overexpression Lysate ...
Gastrin Overexpression Lysate
NBL1-10978
Species: Hu
Applications: WB
Proteins
Recombinant Human Gastrin GST ...
Recombinant Human Gastrin GST (N-T...
H00002520-P01
Species: Hu
Applications: WB, ELISA, PA, PAGE, AP

Description

Gastrin, which is normally formed by mucosal cells in the gastric antrum and by the D cells of the pancreatic islets, is a hormone whose main function is to stimulate secretion of HCl by the gastric mucosa. HCl, in turn, inhibits gastrin formation. Gastrin also stimulates smooth muscle contraction and increases blood circulation and water secretion in the stomach and intestine. Gastrin is regulated by epidermal growth factor in both mice and humans. Gastrin is excreted in excess by pancreatic tumors in the Zollinger- Ellison syndrome. Gastrin maps to human chromosome 17q-21. Gastrin- Releasing Peptide (GRP) stimulates the release of gastrin as well as other gastrointestinal hormones, in addition to acting as an autocrine growth factor for certain cell types. High levels of GRP are found in the human lung just after birth and levels decrease thereafter in parallel with the observed disease in a number of pulmonary neuroendocrine cells. GRP is known to promote lung tumorigenesis in model systems and, interestingly, is induced by retinoic acid. GRP is involved in several functions with the hypothalamus, and is thought to play a role in regulating pituitary hormone secretion. GRP maps to human chromosome 18q21.

Bioinformatics

Uniprot Human
Product By Gene ID 2520
Alternate Names
  • GAS
  • gastrin

PTMs for Gastrin

Learn more about PTMs related to Gastrin.

Phosphorylation
Cleavage
Amidation
Oxidation

Bioinformatics Tool for Gastrin

Discover related pathways, diseases and genes to Gastrin. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
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