gamma H2AX Products



Histone H2AX is a 14 kDa ubiquitous member of the H2A histone family. H2A.X contains an evolutionary conserved SQ motif at the C-terminus in eukaryotes. Serine 139 within this motif becomes rapidly phosphorylated to yield a form known as gamma-H2AX in response to double-strand DNA damage. The response of eukaryotic cells to double-strand breaks in genomic DNA includes the sequestration of many factors into nuclear foci. H2AX becomes extensively phosphorylated within 1-3 minutes of DNA damage and forms foci at break sites.


Entrez Human
Uniprot Human
Product By Gene ID 3014
Alternate Names
  • H2A histone family member X
  • H2AFX
  • H2AX
  • Histone H2A.x
  • Histone H2AX
  • YH2AX
  • H2A/X
  • H2a/x
  • H2A.X
  • H2AX histone
  • H2A histone family, member X

Research Areas for gamma H2AX

Find related products by research area and learn more about each of the different research areas below.

Checkpoint signaling
DNA Double Strand Break Repair
DNA Repair
Mitotic Regulators

Bioinformatics Tool for gamma H2AX

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Related gamma H2AX Blog Posts

Check out the latest blog posts on gamma H2AX.
Further unraveling the role of gamma H2AX in DNA damage response
Our genome experiences a moderate amount of DNA damage in our cells on a daily basis.  This DNA damage can be in response to external environmental factors, or be a result of our internal metabolic processes going awry.  While normal rates of DNA ...    Read more.
Read more gamma H2AX related blogs.