G6PC2 Products

Description

G6PC2 encodes an enzyme belonging to the glucose-6-phosphatase catalytic subunit family. These enzymes are part of a multicomponent integral membrane system that catalyzes the hydrolysis of glucose-6-phosphate, the terminal step in gluconeogenic and glycogenolytic pathways, allowing the release of glucose into the bloodstream. The family member encoded by this gene is found in pancreatic islets and does not exhibit phosphohydrolase activity, but it is a major target of cell-mediated autoimmunity in diabetes. Several alternatively spliced transcript variants of this gene have been described, but their biological validity has not been determined. [provided by RefSeq]. Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1). Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

Bioinformatics

Entrez	57818 Human
Uniprot	NM_021176 Human
Product By Gene ID	57818
Alternate Names	EC 3.1.3.9 G6Pase 2 G-6-Pase 2 glucose-6-phosphatase 2 glucose-6-phosphatase, catalytic, 2 IGRPMGC141936 islet-specific G6CP-related protein Islet-specific glucose-6-phosphatase catalytic subunit-related protein islet-specific glucose-6-phosphatase-related protein